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Archive for category: Research Publications

Polyphenols from grape and blueberry improve episodic memory in healthy elderly with lower level of memory performance: a bicentric double-blind, randomized, placebo-controlled clinical study.

Bensalem J, Dudonné S, Etchamendy N, et al. J Gerontol A Biol Sci Med Sci. 2018 Jul 19.


Supplementation with polyphenol-rich extracts from grape and blueberry improved age-related episodic memory decline, in elderly subjects with the highest cognitive impairments.

Effect of Vitamin D Supplementation on 25(OH)D Status in Elite Athletes With Spinal Cord Injury.

Pritchett K, Pritchett RC, Stark L, et al. Int J Sport Nutr Exerc Metab. 2018 Sep 8:1-6.


Weekly vitamin D supplementation increased vitamin D concentrations in elite athletes with spinal cord injury and improved handgrip strength in 62% of participants, post supplementation.

Strawberry and cranberry polyphenols improve insulin sensitivity in insulin-resistant, non-diabetic adults: a parallel, double-blind, controlled and randomised clinical trial.

Paquette M, Medina Larqué AS, Weisnagel SJ, et al. Br J Nutr. 2017 Feb;117(4):519-531.


A 6-week dietary intervention with 333 mg of polyphenols from strawberries and cranberries improved insulin sensitivity in overweight and obese, non-diabetic, insulin-resistant subjects but was not effective in improving other cardiometabolic risk factors.

Gut microbiota composition in relation to the metabolic response to 12-week combined polyphenol supplementation in overweight men and women.

Most J, Penders J, Lucchesi M, et al. Eur J Clin Nutr. 2017 Sep;71(9):1040-1045.


Epigallocatechin-3-gallate and resveratrol supplementation significantly decreased Bacteroidetes in men but not in women.

Melatonin‐micronutrients Osteopenia Treatment Study (MOTS): a translational study assessing melatonin, strontium (citrate), vitamin D3 and vitamin K2 (MK7) on bone density, bone marker turnover and health related quality of life in postmenopausal osteopenic women

Maria S, Swanson M, Enderby L, et al. AGING. 2017.


In postmenopausal osteopenic women, supplementation with melatonin, strontium, vitamin D3 and vitamin K2 increased bone mineral density, reduced bone turnover and improved sleep quality, compared to placebo, over the course of a year.

A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (ComparED) Study.

Allaire J, Couture P, Leclerc M, et al. Am J Clin Nutr. 2016 Aug;104(2):280-7.


DHA is more effective than EPA in modulating specific markers of inflammation, as well as blood lipids, in men and women with abdominal obesity and low-grade systemic inflammation.

Effects of a systemic enzyme therapy in healthy active adults after exhaustive eccentric exercise: a randomized, two-stage, double-blinded, placebo-controlled trial.

Marzin T, Lorkowski G, Reule C, et al. 2017.


Wobenzym® plus supplementation before and after exercise increased maximum concentric strength in medium performance athletes and improved inflammatory, metabolic and immune biomarkers in all subjects.